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"And there's minimal evidence on the side effects or consequences of long-term or frequent dosing." "It's great to see that we're on this route of health, wellness and recovery, but we need more evidence and research before we can make a true recommendation," he said

The structural data supports an ability of the bypass motif to transition between structured and unstructured conformations in the absence of the allosteric constraint from a RAMP protein

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Most cases resolved without treatment discontinuation